Sandia National Laboratories R&D S&E, Biological Sciece (Early/Mid-Career) in Livermore, California
We are seeking an energetic and independent scientist with expertise in metabolic engineering to join our team in the Biomass Science and Conversion Technologies Department. This individual will join a multi-national lab consortia working to establish an Agile Biofoundry that can rapidly optimize the production of biofuels and bioproducts. Primary responsibilities will entail designing metabolic pathways for the conversion of lignocellulosic biomass into bioproducts, introducing these pathways into bacteria or fungi, optimizing bioproduct production through host engineering, and bench-scale testing of bioproduct titers, rates, and yields.
- Recent PhD in Molecular Biology, Microbiology, Cell Biology, Biochemical Engineering, Enzymology, or related fields.
- Between 3-5 years of experience with metabolic engineering of fungi and/or bacteria to produce bioproducts.
- Background in molecular biology, including the ability to design and construct multi-gene expression systems, screen clone libraries, transformation, heterologous gene expression, gene knockouts, DNA, RNA and protein purification, and familiarity with analytical techniques used to quantify levels of enzymes and metabolites.
- Strong personal, verbal and written communication skills
- Demonstrated track record of publishing in the peer-reviewed scientific literature.
- Demonstrated ability to conduct experiments independently, maintain appropriate records and manage data.
- Familiarity with microbial deconstruction and metabolism of lignocellulose.
- Familiarity with terpene and/or lipid biosynthetic pathways
- Experience using bioinformatics tools to analyze genomic, transcriptomic, metabolomic and proteomic datasets and use them to generate detailed metabolic maps.
- Background in sugar metabolism and knowledge of analytical tools that utilize GC, LC, and mass spectrometry.
- Familiarity and working knowledge of DOE biofuel programs.
The Biomass Science and Conversion Technology department is dedicated to developing and advancing innovative technologies for producing the next generation of biofuels. Our multidisciplinary staff represents a diverse range of backgrounds and skill sets: molecular biology, chemistry, chemical and biochemical engineering, biophysics, computational science, and biochemistry. We partner broadly with other Sandia departments as well as other national laboratories, industry, and universities to develop practical, science-based solutions to national energy goals. We also play an essential role in the DOE Joint BioEnergy Institute (JBEI), one of three Bioenergy Research Centers in the Nation advancing the next generation of biofuel technologies.
Sandia National Laboratories is the nation’s premier science and engineering lab for national security and technology innovation, with teams of specialists focused on cutting-edge work in a broad array of areas. Some of the main reasons we love our jobs:
- Challenging work withamazingimpact that contributes to security, peace, and freedom worldwide
- Extraordinary co-workers
- Some of the best tools, equipment, and research facilities in the world
- Career advancement and enrichment opportunities
- Flexible schedules, generous vacations,strongmedical and other benefits, competitive 401k, learning opportunities, relocation assistance and amenities aimed at creating a solid work/life balance*
World-changing technologies. Life-changing careers. Learn more about Sandia at: http://www.sandia.gov
*These benefits vary by job classification.
This position does not currently require a Department of Energy (DOE)-granted security clearance.
Sandia will conduct a pre-employment drug testing, and a pre-employment background review that includes personal reference checks, law enforcement record checks, and employment and education verifications. Further, employees in New Mexico must pass a U.S. Air Force background screen for access to the work site. Substance abuse or illegal drug use, falsification of information, criminal activity, serious misconduct or other indicators of untrustworthiness can cause access to be denied or terminated, rendering the inability to perform the duties assigned and resulting in termination of employment.
If hired without a clearance, and one subsequently becomes required or you bid on positions that require a DOE-granted security clearance, a pre-processing background review that includes personal reference checks, law enforcement record and credit checks, and employment and education verifications may be conducted prior to a required federal background investigation. Applicants for DOE-granted security clearances must be U.S. citizens and be able to obtain and maintain the appropriate DOE security clearance as required for the position.
Equal opportunity employer/Disability/Vet/GLBT